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The Lab was founded on basis of Pharmacokinetics group in 1986.
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Ever since it is headed by professor Vladimir P. Zherdev (birthdate 1946).
tel.: (495) 601-2157 |
Major lines of scientific research:
- Experimental pharmacokinetic studies on novel drugs designed on the basis of pharmacologically active substances;
- Clinical pharmacokinetic studies on novel substances, including phase I clinical trials;
- Biotransformation assessment of different drugs;
- Experimental and clinical study on relationship between pharmacokinetic and pharmacodynamic parameters of different drugs;
- Biopharmaceutical issues evaluation aimed to design the optimal drug formulations;
- Bioavailability assessment of reproduced drugs in experiment and bioequivalence evaluation in clinic according to RF Ministry of Health Care Pharmacological Committee decision;
- Education and training of specialists in pharmacokinetics;
17 Ph.D and 3 Doctor theses were supported in the Lab.
The following affiliations are embraced by scientific collaboration:
- Republic of Kazakhstan, Karaganda State Medical Academy, Department of Clinical Pharmacology (chaired by Professor A. Gulyaev);
- Moscow Center of Scientific & Applied Sport Medicines, Laboratory of Clinical Pharmacology (chaired by Professor R. Seyfulla);
- Sechenov' Moscow Medical Academy, Department of Clinical Pharmacology (Professor A. Starodubtsev);
- Department of Cerebrovascular Disorders Pharmacology (headed by Professor R. Mirzoyan);
- Department of Clinical Pharmacology (headed by Professor G. Neznamov);
- Department of Isotope Research Methods (headed by Professor G. Kovalev);
- Department of Experimental Technology (headed by Professor B. Pyatin);
- Department of Psychopharmacology (headed by Professor T. Voronina);
Recent publications:
- AK Sariev, EV Lun'shina, VP Zherdev, and NR Mirzoian. Correlations of pharmacokinetics and pharmacodynamics of a combined preparation containing pyrrolidone and pyroglutamic acid.
Eksp Klin Farmakol, Mar 2006; 69(2): 58-61.
- V.P. Zherdev, et al. «The role of pharmacokinetic researches in optimisation of new anxiolytics drug formulations».// Abstr. Of the 15 World Congress of Pharmacology. 2006. p. 213, China.
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